Table 2.
Echocardiographic parameters of all patients with chronic organic mitral regurgitation and the comparisons between patients with and without pulmonary hypertension
| Variables | Total (n = 154) | No PH (n = 113) | PH (n = 41) | P-value |
|---|---|---|---|---|
| RVSP (mmHg) | 43.2 ± 17.7 | 34.6 ± 7.3 | 66.8 ± 16.1 | <0.001 |
| PAEDP (mmHg) | 14.1 ± 6.5 | 11.6 ± 3.8 | 20.8 ± 7.6 | <0.001 |
| Mean PAP (mmHg) | 25.8 ± 10.3 | 21.5 ± 6.9 | 36.8 ± 9.5 | <0.001 |
| PVR (Wood unit) | 2.5(1.0–9.0) | 2.2(1.0–25.2) | 4.0(1.9–9.0) | <0.001 |
| EROA (mm2) | 61.8(22.0–250.9) | 55.9(22.0–250.9) | 87.5(27.0–225.1) | <0.001 |
| RVol (ml) | 107.1 ± 51.8 | 99.1 ± 48.4 | 129.1 ± 55.2 | 0.001 |
| Severe MR | 123(79.9) | 85(75.2) | 38(92.7) | 0.017 |
| LVEF (%) | 68.1 ± 5.9 | 68.4 ± 5.9 | 67.2 ± 6.1 | 0.231 |
| LAV (ml) | 109.8(44.5–653.4) | 94.3(44.5–486.3) | 147.1(70.9–653.4) | <0.001 |
| LAV index (ml/m2) | 67.1(24.7–391.3) | 59.3(24.7–276.3) | 88.4(42.0–391.3) | <0.001 |
| LA diameter (mm) | 52.9 ± 11.1 | 50.0 ± 9.6 | 60.8 ± 11.1 | <0.001 |
| LVDd (mm) | 56.6 ± 6.7 | 56.2 ± 6.5 | 58.8 ± 6.3 | 0.029 |
| LVSd (mm) | 33.8 ± 5.7 | 33.3 ± 5.9 | 35.2 ± 4.8 | 0.072 |
| LVEDV (ml) | 113.3 ± 33.0 | 110.2 ± 32.2 | 122.0 ± 33.7 | 0.049 |
| LVESV (ml) | 36.5 ± 13.6 | 35.0 ± 13.2 | 40.5 ± 13.9 | 0.027 |
| LVMI (g/m2) | 146.4 ± 43.4 | 139.4 ± 38.5 | 165.7 ± 50.7 | 0.001 |
| E (cm/sec) | 119.2 ± 33.8 | 108.7 ± 28.6 | 149.0 ± 29.8 | <0.001 |
| A (cm/sec) | 70.8 ± 24.1 | 71.1 ± 24.7 | 69.3 ± 21.9 | 0.743 |
| E/A | 1.8 ± 0.8 | 1.6 ± 0.7 | 2.3 ± 1.0 | <0.001 |
| DT (ms) | 201.9 ± 48.6 | 208.5 ± 50.5 | 182.7 ± 37.1 | 0.005 |
| E/E’ | 15.9 ± 6.1 | 14.4 ± 5.3 | 20.7 ± 6.0 | <0.001 |
| TAPSE (mm) | 22.7 ± 4.5 | 23.3 ± 4.3 | 21.2 ± 5.0 | 0.011 |
| St’ (cm/sec) | 12.2 ± 2.2 | 12.3 ± 2.0 | 11.7 ± 2.7 | 0.148 |
Data are expressed as number (percentage), median (min-max) or mean ± standard deviation
P-values are for comparisons between 2 groups
A peak late diastolic velocity of mitral inflow, DT, deceleration time, E peak early diastolic velocity of mitral inflow, E’ tissue Doppler peak early diastolic velocity of medial mitral annulus, EROA effective regurgitant orifice area, LA left atrium, LAV left atrial volume, LV left ventricle, LVDd left ventricular end-diastolic diameter, LVEF left ventricular ejection fraction, LVSd left ventricular end-systolic diameter, LVEDV left ventricular end-diastolic volume, LVESV left ventricular end-systolic volume, LVMI left ventricular mass index, MR mitral regurgitation, PAEDP pulmonary artery end-diastolic pressure, PAP pulmonary artery pressure, PH pulmonary hypertension, PVR pulmonary vascular resistance, RVol regurgitant volume, RVSP right ventricular systolic pressure, S t ’ tissue Doppler peak systolic velocity of lateral tricuspid annulus, TAPSE tricuspid annular plane systolic excursion