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. 2016 Jun 22;16:141. doi: 10.1186/s12872-016-0306-3

Table 6.

Clinical characteristics and echocardiographic parameters of patients with chronic organic mitral regurgitation and the comparisons between subgroups of patients according to the symptom status and the severity of mitral regurgitation

Variables Total (N = 154) Symptom status Severity of MR
Symptomatic (N = 58) Asymptomatic (N = 96) P-value Severe MR (N = 123) Non-severe MR (N = 31) P-value
Symptomatic 58 (37.7) - - - 46 (37.4) 12 (38.7) 1.0
Severe MR 123(79.9) 46 (79.3) 77 (80.2) 1.0 - - -
Age (years) 55.0 ± 16.4 58.3 ± 16.2 53.0 ± 16.3 0.051 55.3 ± 16.1 53.9 ± 17.9 0.684
Male gender 93(60.4) 30(51.7) 63(65.6) 0.087 82(66.7) 11(35.5) 0.002
Atrial fibrillation 45(29.4) 25(43.1) 20(21.1) 0.004 34(27.9) 11(35.5) 0.406
LVDd (mm) 56.9 ± 6.6 57.7 ± 7.5 56.3 ± 5.9 0.245 58.3 ± 6.3 51.1 ± 4.1 <0.001
LVSd (mm) 33.8 ± 5.7 34.5 ± 6.3 33.4 ± 5.3 0.238 34.5 ± 5.8 31.0 ± 4.4 <0.001
LVEDV (ml) 113.3 ± 33.0 114.2 ± 36.4 112.8 ± 30.9 0.810 119.5 ± 32.3 89.0 ± 22.9 <0.001
LVESV (ml) 36.5 ± 13.6 37.8 ± 15.5 35.7 ± 12.3 0.382 38.0 ± 13.8 30.4 ± 10.5 0.005
LVMI (g/m2) 146.4 ± 43.44 163.8 ± 50.7 135.5 ± 34.3 <0.001 154.6 ± 42.5 113.3 ± 29.8 <0.001
E/E’ 15.9 ± 6.1 18.0 ± 6.1 14.8 ± 5.9 0.002 16.6 ± 6.2 13.3 ± 5.0 0.008
TAPSE (mm) 22.7 ± 4.6 21.5 ± 4.6 23.4 ± 4.4 0.010 22.9 ± 4.5 22.0 ± 4.9 0.307
EROA (mm2) 61.8(22.0–250.9) 78.7(23.0–250.9) 56.5(22.0–225.1) 0.080 72.0(40.0–250.9) 28.9(22.0–44.9) <0.001
RVol (ml) 102.1(20.3–336.2) 114.8(36.2–336.2) 95.5(20.3–267.9) 0.058 113.3(61.3–336.2) 48.1(20.3–75.0) <0.001
LAV index (ml/m2) 67.1(24.7–391.3) 80.4(30.3–391.3) 62.5 (24.7–276.3) 0.007 71.7(30.3–391.3) 46.3(24.7–145.0) <0.001
RVSP (mmHg) 43.2 ± 17.7 49.0 ± 18.0 39.6 ± 16.5 0.001 44.9 ± 18.7 36.3 ± 10.4 0.001

Data are expressed as number (percentage), median (min-max) or mean ± standard deviation

P-values are for comparisons between 2 groups

E peak early diastolic velocity of mitral inflow, E’ tissue Doppler peak early diastolic velocity of medial mitral annulus, EROA effective regurgitant orifice area, LAV left atrial volume, LVDd left ventricular end-diastolic diameter, LVSd left ventricular end-systolic diameter, LVEDV left ventricular end-diastolic volume, LVESV left ventricular end-systolic volume, LVMI left ventricular mass index, MR mitral regurgitation, RVol regurgitant volume, RVSP right ventricular systolic pressure, TAPSE tricuspid annular plane systolic excursion