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. 2016 Jun 23;13:162. doi: 10.1186/s12974-016-0630-7

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — CCL20 blockade improves neurological outcome after SCI. a Analysis of locomotor BBB scores after SCI (from 1 to 28 days post-injury). A significant improvement in hindlimb motor function is observed in the CCL20 mAb group compared with the injury control groups from 7 days post-injury. b The water content data shows that CCL20 blockade significantly alleviates spinal cord edema at 3 days post-SCI. ⁺ P < 0.05, compared with the sham group; ^* P < 0.05, compared with the CCL20 mAb group; &P < 0.05, compared with the isotype control group