Table 9.

Mean Change in Outcome Scores for Kellgren-Lawrence (K-L) Grades at 6 and 12 Months.

	K-L Grade 2 (n = 235), Mean (95% CI)	K-L Grade 3 (n = 353), Mean (95% CI)	P
Mean change in VAS pain target knee
6 months	−24.87 (−28.81, −20.93)	−17.19 (−20.55, −13.82)	0.004
12 months	−34.24 (−38.49, −29.98)	−27.22 (−30.94, −23.51)	0.016
Mean change in WOMAC pain
6 months	−21.08 (−24.73, −17.43)	−13.22(−16.01, −10.43)	0.001
12 months	−29.44 (−33.26, −25.62)	−19.62 (−22.94, −16.31)	<0.001
Mean change in WOMAC stiffness
6 months	−20.02 (−23.90, −16.15)	−14.09 (−17.36, −10.82)	0.023
12 months	−30.07 (–34.40, −25.75)	−19.46 (−23.28, −15.63)	<0.001
Mean change in WOMAC disability
6 months	−19.39 (−22.88, −15.89)	−13.38 (−15.98, −10.78)	0.006
12 months	−28.55 (−32.42, −24.68)	−19.86 (−22.96, −16.76)	0.001
Mean change in global VAS assessment
6 months	−23.21 (−27.08, −19.34)	−15.73 (−18.84, −12.61)	0.003
12 months	−33.29 (−37.58, −29.01)	−24.94 (−28.52, −21.36)	0.003

CI = confidence interval; VAS, visual analog scale; WOMAC = Western Ontario and McMaster Universities Arthritis Index.