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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Biodemography Soc Biol. 2016;62(1):1–18. doi: 10.1080/19485565.2015.1068106

Table 1.

Heritability estimates from applications of GCTA.

Outcome h2(SE) Sample
Size		 Reference
Anthropometric Phenotypes
Height 0.44 (0.09) 2,000 Speed et al. 2012
Height 0.35 (0.12) 3,154 Plomin et al. 2012
Height 0.32 (0.06) 6,379 Conley et al. 2014
Weight 0.42 (0.12) 3,154 Plomin et al. 2012
BMI 0.43 (0.10) 4,233 Boardman et al. 2014
BMI 0.31 (0.07) 6,320 Conley et al. 2014
Medical/Clinical Phenotypes
Type 1 Diabetes 0.73 (0.06) 2,000 Speed et al. 2012
Type 1 Diabetes 0.28 (0.04) 2,599 Lee et al. 2011
Type 2 Diabetes 0.35 (0.06) 2,000 Speed et al. 2012
Rheumatoid Arthritis 0.57 (0.06) 2,000 Speed et al. 2012
Crohn Disease 0.61 (0.08) 2,599 Lee et al. 2011
Crohn Disease 0.54 (0.06) 2,000 Speed et al. 2012
Coronary Artery Disease 0.39 (0.06) 2,000 Speed et al. 2012
Pediatric Obesity 0.37 (0.15) 3,152 Llewellyn et al. 2013
Hypertension 0.42 (0.06) 2,000 Speed et al. 2012
Parkinson's Disease (Early-Onset) 0.15 (0.14) 7,096 Keller et al. 2012
Parkinson's Disease (Late-Onset) 0.31 (0.07) 7,096 Keller et al. 2012
Parkinson's Disease (All Types) 0.27 (0.05) 7,096 Keller et al. 2012
Parkinson's Disease 0.22 (0.02) 3,426 Do et al, 2011
Multiple Sclerosis 0.3 (0.02) 1,854 Watson et al. 2012
Cognitive Phenotypes
General Cognitive Ability 0.35 (0.12) 3,154 Plomin et al. 2012
General Cognitive Ability 0.29 (0.05) 6,609 Marioni et al. 2014
Nonverbal Cognitive Ability 0.20 (0.11) 3,154 Plomin et al. 2012
Verbal Cognitive Ability 0.26 (0.11) 3,154 Plomin et al. 2012
Language Ability 0.29 (0.12) 3,154 Plomin et al. 2012
Intelligence (age 7–12) 0.60 (0.26) 2,875 Trzaskowski et al. 2014
Intelligence 0.51 (0.02) 3,511 Davies et al. 2011
Intelligence from Childhood to
Old Age		 0.24 (0.20) 1,940 Deary et al. 2012
IQ (Age 12) 0.32 (0.14) 3,000 Trzaskowski et al. 2014
IQ (Age 7) 0.28 (0.17) 3,000 Trzaskowski et al. 2014
Psychological Phenotypes
Bipolar Disorder 0.59 (0.06) 2,000 Speed et al. 2012
Bipolar Disorder 0.37 (0.04) 2,599 Lee et al. 2011
ADHD 0.42 (0.13) 1,040 Yang et al. 2013
Adult Anti-Social Behavior 0.55 (0.41) 2,172 Tielbeek et al. 2012
Depression 0.19 (0.10) 4,233 Boardman et al. 2014
Major Depressive Disorder 0.32 (0.09) 4,605 Lubke et al. 2012
Behavioral Disinhibition 0.19 (0.16) 3,452 Vrieze et al. 2013
Neuroticism 0.06 (0.03) 12,000 Vinkhuyzen et al. 2012
Borderline Personality Features 0.23 (0.09) 7, 125 Lubke et al. 2014
Callous-Emotional Behavior 0.07 (0.12) 2,930 Viding et al. 2013
Extraversion 0.12 (0.03) 12,000 Vinkhuyzen et al. 2012
Anxiety Related Behaviors 0.01–0.12
(0.12)		 2,810 Trzaskowski et al. 2013
Substance Dependency Phenotypes
Drug Use 0.22 (0.16) 3,452 Vrieze et al. 2013
Drug Dependence 0.36 (0.13) 2,596 Palmer et al. 2014
Dependence Vulnerability 0.33 (0.13) 2,596 Palmer et al. 2014
Problematic Drug Use 0.25 (0.13) 2,596 Palmer et al. 2014
Alcohol Consumption 0.16 (0.16) 3,452 Vrieze et al. 2013
Alcohol Dependence 0.12 (0.16) 3,452 Vrieze et al. 2013
Nicotine Use/Dependence 0.18 (0.16) 3,452 Vrieze et al. 2013
Sociological/Health Behavior/Educational Phenotypes
Socioeconomic Background 0.18 (0.05) 6,533 Marioni et al. 2014
Socioeconomic Status (age 2) 0.18 (0.12) 3,000 Trzaskowski et al. 2014
Socioeconomic Status (age 7) 0.19 (0.12) 3,000 Trzaskowski et al. 2014
Subjective Well-Being 0.05–0.10
(0.05–0.10)		 11,500 Rietveld et al. 2013a
Reporting Stressful Life Events 0.3 (0.15) 2,578 Power et al. 2013
Self-Rated Health 0.18 (0.10) 4,233 Boardman et al. 2014
Moderate to Vigorous Activity 0.17 (0.09) 4,244 Richmond et al. 2014
Sedentary Time 0.25 (0.09) 4,244 Richmond et al. 2014
Total Physical Activity 0.21 (0.10) 4,244 Richmond et al. 2014
Education 0.21 (0.05) 6,578 Marioni et al. 2014
Education 0.33 (0.10) 4,233 Boardman et al. 2014
Education 0.17 (0.07) 6,414 Conley et al. 2014