Table 3.

Adverse drug event outcomes in OMOP mapped to MeSH terms at different abstraction levels

Aggregation	ORIGINAL	LOW (IC 7–10)	MEDIUM (IC 4.5–7)	HIGH (IC 1–5.5)	MeSH 2nd level
Acute kidney injury	Acute kidney injury, Kidney tubular necrosis, acute	Acute kidney injury D058186 (5th level) IC: 9.34	Kidney Diseases D007674 (3rd level) IC: 5.73	Urologic Diseases D014570 (2nd level) IC: 5.16	Urologic Diseases D014570 (2nd level) IC: 5.16
Acute Liver injury	Drug-induced liver injury, Drug-induced liver injury, chronic	Drug-Induced Liver Injury D056486 (3rd level) IC: 9.87	Liver Diseases D008107 (2nd level) IC: 5.64	Digestive System Diseases D004066 (1st level) IC: 4.01	Liver Diseases D008107 (2nd level) IC: 5.64
Acute Myocardial Infarction	Myocardial infarction, Anterior wall MI, Inferior wall MI, Myocardial stunning, Shock, cardiogenic	Myocardial infarction D009203 (4th level) IC: 7.22	Myocardial Ischemia D017202 (3rd level) IC: 5.94	Heart Diseases D006331 (2nd level) IC: 4.61	Heart Diseases D006331 (2nd level) IC: 4.61
GI bleed	GI Hemorrhage, Hematemesis, Melena, Peptic ulcer hemorrhage	Gastrointestinal Hemorrhage D006471 (3rd level) IC: 9.00	Gastrointestinal Diseases D005767 (2nd level) IC: 4.87	Digestive System Diseases D004066 (1st level) IC: 4.01	Gastrointestinal Diseases D005767 (2nd level) IC: 4.87