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. 2016 Jun 23;17:250. doi: 10.1186/s12859-016-1080-z

Table 6.

Adverse event signals for drugs detected by GEA and PRR

p-value GEA IC 7–10 GEA IC 4.5–6 GEA IC 1–5.5 PRR 2nd PRR IC 7–10 PRR
<0.1 43702 (22073) 10585 (7634) 12875 (6157) 30547 61108 >1
<0.05 35953 (17140) 9249 (6840) 11453 (5356) 24834 52377 >1.5
<0.005 23059 (10122) 6867 (4931) 8594 (3623) 10810 26953 >5

Adverse event signals for drugs (ATC ingredient names) detected by GEA and PRR using different thresholds at different aggregation levels. The number in bold indicates the unique adverse event association signals found using the optimal configuration (GEA at IC 7–10 with p < 0.005) as determined by the overall performance assessment