Table 1.
Baseline Characteristics of Current Study Participants, According to LPIR Score
| Lower Tertile (n=4002) | Middle Tertile (n=4076) | Upper Tertile (n=3840) | |
|---|---|---|---|
| Age (years) | 68 (63–73) | 66 (60–71) | 64 (58–69) |
| Women | 2012 (50.3) | 1558 (38.2) | 764 (19.9) |
| Rosuvastatin | 2019 (50.5) | 1985 (48.7) | 1905 (49.6) |
| Ethnic Origin | |||
| White | 3217 (80.4) | 3219 (80.7) | 3342 (87.1) |
| Black | 411 (10.3) | 252 (6.2) | 79 (2.1) |
| Asian | 61 (1.5) | 67 (1.6) | 49 (1.3) |
| Hispanic | 267 (6.7) | 432 (10.6) | 361 (9.4) |
| Other | 45 (1.1) | 34 (0.8) | 8 (0.2) |
| Current smoker | 593 (14.8) | 594 (14.6) | 566 (14.8) |
| Hypertension | 2145 (53.6) | 2268 (55.7) | 2264 (59.0) |
| Metabolic syndrome | 698 (17.6) | 1609 (39.8) | 2578 (67.5) |
| BMI (kg/m2) | 26.7 (23.8–30.1) | 28.6 (25.9–32.1) | 30.0 (27.3–33.3) |
| Family history of diabetes | 886 (23.5) | 984 (25.6) | 998 (27.3) |
| Highest level of education | |||
| Up to high school | 2335 (58.4) | 2330 (57.2) | 1932 (50.3) |
| Some college | 735 (18.4) | 777 (19.1) | 866 (22.6) |
| College graduate | 589 (14.7) | 610 (15.0) | 614 (16.0) |
| Post graduate | 341 (8.5) | 355 (8.7) | 426 (11.1) |
| Exercise | |||
| Rare or never | 1988 (49.7) | 2029 (49.8) | 1865 (48.6) |
| Once or less per week | 480 (12.0) | 493 (12.1) | 544 (14.2) |
| Two to three times per week | 742 (18.6) | 730 (17.9) | 732 (19.1) |
| Four to seven times per week | 790 (19.8) | 822 (20.1) | 698 (18.2) |
| Fasting glucose (mg/dL) | 92 (86–99) | 95 (89–102) | 97 (90–105) |
| Glycated hemoglobin (%) | 5.6 (5.4–5.9) | 5.7 (5.4–5.9) | 5.7 (5.4–5.9) |
| hsCRP (mg/L) | 4.1 (2.7–7.0) | 4.2 (2.8–7.0) | 4.0 (2.8–6.3) |
| LDL cholesterol (mg/dL) | 109 (95–119) | 110 (96–120) | 109 (95–119) |
| HDL cholesterol (mg/dL) | 61 (57–71) | 49 (42–57) | 41 (36–47) |
| Triglycerides (mg/dL) | 87 (69–111) | 119 (93–157) | 173 (130–237) |
| Triglyceride/HDL cholesterol ratio | 1.45 (1.05–1.98) | 2.40 (1.77–3.38) | 4.24 (2.96–6.18) |
| Non-HDL cholesterol (mg/dL) | 127 (113–139) | 135 (120–146) | 144 (130–157) |
| Apolipoprotein B (mg/dL) | 102 (91–112) | 109 (97–121) | 118 (106–130) |
Data are median (IQR) or n (%). Percentages may not add up because of rounding off. BMI body-mass index; hsCRP high sensitivity C-reactive protein; LDL low-density lipoprotein; HDL high-density lipoprotein.
p<0.001 with exception of rosuvastatin (p=0.29), current smoker (p=0.95), exercise (p=0.082), hsCRP (p=0.002), and LDL cholesterol (p=0.18), from Wilcoxon rank sum test for quantitative variables and χ2 tests for qualitative variables.
LPIR tertiles as follows: lower tertile (score of 40 or lower); middle tertile (41-62); upper tertile (score of 62 or higher).