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. Author manuscript; available in PMC: 2017 May 23.
Published in final edited form as: Annu Rev Pathol. 2016 Feb 24;11:365–393. doi: 10.1146/annurev-pathol-012615-044241

Figure 4.

Figure 4

Timeline of EoE research. EoE has been studied over the last 20 years, with the majority of findings occurring within the last decade. These findings have advanced clinical and mechanistic insights into disease epidemiology, pathogenesis, and treatment. Abbreviations: CAPN14, calpain 14; EoE, eosinophilic esophagitis; IL, interleukin; TGF-β, transforming growth factor β; TSLP, thymic stromal lymphopoietin; miRNAs, microRNAs; PPI-REE, proton-pump inhibitor-responsive esophageal eosinophilia.