Table 2. Chronic obstructive pulmonary disease (COPD) comorbidity prevalence from studies that included multiple comorbidities in their analysis.
First auther[ref] | ||||||||||
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Divo [46] | Vanfleteren [48] | Mapel [45] | Cazzola [44] | Van Manen [49] | Schnell [42] | |||||
| ||||||||||
Disease ascertainment | Self-reported | Measured | Administrative database | Administrative database | Administrative database | Self-reported/measured | ||||
| ||||||||||
COPD | Control | COPD | Control | COPD | Control | COPD | Control | |||
Subjects n | 1659 | 213 | 200 | 200 | 15 000 | 325 000 | 290 | 421 | 995 | 14828 |
Hypertension | 52.3 | 48 | 45 | 36.5 | 22.7 | 21.4 | 60.4 | 52.2 | ||
Hyperlipidaemia | 43.5 | 36 | 47.6 | 41.3 | ||||||
CAD | 30.2 | 9 | 22 | 14.5 | 15.9 | 6.6 | ||||
Obesity | 29.0 | 23 | 40.3 | 33.5 | ||||||
DJD | 28.7 | 22 | 19.5 | 54.6 | 36.9 | |||||
Muscle wasting | 28 | |||||||||
Diabetes mellitus | 21.5 | 54 | 8 | 6.5 | 18.7 | 10.5 | 7.1 | 4.6 | 16.3 | 12.8 |
GORD | 17.7 | |||||||||
PAD | 16.7 | 53 | 5.5 | 1.7 | ||||||
Depression | 16.7 | 16 | 17 | 13 | 7.4 | 5.3 | 8.7 | 4.4 | 20.6 | 12.5 |
CRF | 16.7 | 22 | 1.5 | 1 | 16.2 | 10.5 | ||||
CHF | 15.7 | 13.5 | 2.5 | 7.9 | 2.0 | 12.1 | ||||
Underweight | 15.0 | 14 | ||||||||
Substance abuse | 13.8 | |||||||||
Atrial fibrillation | 13.0 | |||||||||
Anxiety | 11.9 | 21 | 8.6 | 3.8 | ||||||
Erectile dysfunction | 11.7 | |||||||||
Gastric/duodenal ulcer | 11.5 | 32 | 17 | 7.2 | 1.5 | |||||
CVA | 10.7 | 4 | 3.5 | 3.1 | 3.7 | 8.9 | 4.5 | |||
Pulmonary HTN+CP | 10.2 | |||||||||
OSA | 10.1 | |||||||||
Lung cancer | 9.1 | 1.9 | 0.4 | |||||||
Osteoporosis | 8.4 | 31 | 14.8 | 10.8 | 16.9 | 8.5 | ||||
Hypothyroidism | 7.0 | |||||||||
Breast cancer | 7.0 | |||||||||
AAA | 6.5 | |||||||||
Pulmonary fibrosis | 6.1 | |||||||||
DVT | 5.1 | |||||||||
Anaemia | 5 | 9.3 | 6.2 | |||||||
Cardiac arrhythmia | 12 | 9.5 | 13.6 | 6.9 |
Data are presented as % unless otherwise stated. CAD: coronary artery disease; DJD: degenerative joint disease; GORD: gastro-oesophageal reflux disease; PAD: peripheral artery disease; CRF: chronic renal failure; CHF: congestive heart failure; CVA: cerebrovascular accident; HTN: hypertension; CP: cor pulmonale; OSA: obstructive sleep apnoea; AAA: abdominal aortic aneurism; DVT: deep-venous thrombosis.