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. 2016 Jun 23;18:150. doi: 10.1186/s13075-016-1047-5

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Static weight-bearing (SWB) evolution after induction of osteoarthritis (least squares mean ± standard error of the mean). On day 3, the monosodium iodoacetate (MIA) intra-articular injection in the right knee induced asymmetrical weight distribution in the rats injected with MIA (adjusted P value (adj-P) = 0.0024) and rats injected with MIA and punctual lidocaine (MIA-L) (adj-P = 0.0011) compared to rats injected with 0.9 % saline (sham). Subsequently, a statistically significant difference in right hind paw SWB was only observed between the sham and MIA-L groups at days 7 and 21. %BW percentage of body weight. ^a,bSignificant inter-group statistical differences