Table 4.
Mean and standard deviation of the punctate tactile allodynia evaluation by experimental group over time
Experimental group | Days | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
-1 | 3 | 7 | 14 | 21 | ||||||
Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
MIA | 53.8 | 11.2 | 39.2 | 13.1 | 43.1 | 13.7 | 40.0 | 10.0 | 39.8 | 8.5 |
MIA-L | 70.4 | 16.8 | 35.0 | 13.8 | 52.6 | 12.7 | 47.8 | 14.3 | 36.2 | 17.8 |
Sham | 56.3 | 16.9 | 49.0 | 14.8 | 39.2 | 16.6 | 37.0 | 17.6 | 45.6 | 17.0 |
Descriptive statistics of the punctate tactile allodynia evaluation (PTAE) of the right hind paw. The measure was obtained for the three groups (eight animals per group) in grams on days 3, 7, 14, and 21 following the intra-articular injection of monosodium iodoacetate (MIA). Intra-articular injection was performed on day 0 (2 mg of MIA for the MIA and rats injected with monosodium iodoacetate and punctual lidocaine (MIA-L) groups and 0.9 % NaCl for the sham group). The MIA-L group also received an intra-articular injection of lidocaine in the right knee on days 7, 14, and 21, at 25 minutes before the PTAE. SD standard deviation