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. 2016 Jun 23;4:61. doi: 10.1186/s40478-016-0335-2

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Dendrospinal pTDP-43 pathology in the neostriatum and globus pallidus. (a) Low-magnification view of the basal ganglia from a case of Type 2b delineates the putamen and globus pallidus with phosphorylated TDP-43 (pTDP-43) immunoreactivity. (b, c) High-magnification views of the putamen (b) and globus pallidus (c) show numerous pTDP-43-positive granular and dot-like structures. (d) Similar granular and dot-like structures in the globus pallidus are also visualized using phosphorylation-independent anti-TDP-43. Scale bars: a = 500 μm; b-d = 10 μm. GPe = external segment of globus pallidus; GPi = internal segment of globus pallidus