Table 1.
Representative autoantigens involved in autoimmune disease
| Disease | Autoantigen |
|---|---|
| Type I diabetes | Carboxypeptidase H |
| Chromogranin A | |
| Glutamate decarboxylase | |
| Imogen-38 | |
| Insulin | |
| Insulinoma antigen-2 and 2β | |
| Islet-specific glucose-6-phosphatase catalytic subunit related protein (IGRP) | |
| Proinsulin9 | |
| Multiple sclerosis | α-enolase |
| Aquaporin-4 | |
| β-arrestin | |
| Myelin basic protein | |
| Myelin oligodendrocytic glycoprotein | |
| Proteolipid protein | |
| S100-β10 | |
| Rheumatoid arthritis | Citrullinated protein |
| Collagen II | |
| Heat shock proteins | |
| Human cartilage glycoprotein 3912 | |
| Systemic lupus erythematosus | Double-stranded DNA |
| La antigen | |
| Nucleosomal histones and ribonucleoproteins (snRNP) | |
| Phospholipid-β-2 glycoprotein I complex | |
| Poly(ADP-ribose) polymerase | |
| Sm antigens of U-1 small ribonucleoprotein complex11 |
Abbreviation: snRNP, small nuclear ribonucleoprotein.