Figure 2.

(A–D) IVIS images of nude mice with HepG2-luc xenografts prior to intratumoral treatment with 2×10⁴ pfu HSV1716 and at 5, 15, and 32 days post-injection. The remaining two mice with an IVIS signal on day 32 (D) are shown 11 (E) and 17 (F) days after a second intratumoral injection of HSV1716 at 2×10⁴ pfu. (G and H) Six representative control mice on days 0 and 32.

Note: Red circles indicate the region of interest for light determination.

Abbreviation: IVIS, in vivo imaging system.