Table 2.
Representative ARGs in the liver
| ARGs | Function | References |
|---|---|---|
| CYPs | Drug metabolism and alcohol metabolism | 54–57,70 |
| TGF-β1 | HCC development, hepatic fibrosis, hepatic damage, and hepatic regeneration | 66 |
| LXR | Cholesterol homeostasis | 71 |
| VEGF | HCC development and angiogenesis | 12,49 |
| CCRK | HCC development | 75 |
| GRP78/Bip | ER stress and HCC development | 86,92 |
Abbreviations: ARG, androgen-responsive gene; CYP, cytochrome P450; ER, endoplasmic reticulum; HCC, hepatocellular carcinoma; TGF-β1, transforming growth factor β1; LXR, liver-X-receptor; VEGF, vascular endothelial growth factor; CCRK, cell cycle–related kinase; GRP78/Bip, glucose-regulated protein 78 kDa.