Table 3.

HSVs designed for cancer therapy

HSV	HSV gene mutated	Transgenes	References
hrR3	UL39		114
R3616	γ34.5		115
G207	γ34.5, UL39		66,116
NV1020	UL24, UL56		117
OncoVex GM–CSF	γ34.5, ICP47	GM–CSF	60
HF-10			118
L1BR1	US-3		65
FusOn-H2 (HSV-2)	ICP10		69

Abbreviations: GM–CSF, granulocyte–macrophage colony-stimulating factor; HSV, herpes simplex virus.