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. 2015 Aug 26;4:95–107. doi: 10.2147/OV.S66358

Table 3.

Adenovirus vectors tested in dogs with and without spontaneous tumors

Virus vector Dogs (n) Route Outcome (n) Authors, year
Recombinant Ad6 (two constructs) Healthy (3–6) Intramuscular No detrimental effects Peruzzi et al, 201046
Ad6-dTERT Lymphoma (14) Intramuscular Prolonged survival time Peruzzi et al, 201047
Ad-IFNγ Astrocytoma (1) Intratumoral Prolonged survival time Pluhar et al, 201048
AdCD40L Oral melanoma (1) Intratumoral Complete remission (2) von Euler et al, 200849
Dermal melanoma (1)
Melanoma (19) Intratumoral Complete remission (5) Westberg et al, 201350
Partial remission (8)
Stable disease (4)
Progressive disease (2)