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. Author manuscript; available in PMC: 2016 Jun 23.
Published in final edited form as: ACS Nano. 2016 Feb 25;10(3):3015–3041. doi: 10.1021/acsnano.5b07522

Figure 7. Efficient delivery of STAT3 siRNA molecules to tumor cells using HDL.

Figure 7

(A) Schematic of encapsulation of siRNA into HDL after complexation with poly-lysine. (B) A TEM of siRNA-loaded HDL. (C) In vivo antitumor effect of STAT3 siRNA/rHDL in chemosensitive (HeyA8 and SKOV3ip1) and chemoresistant (HeyA8-MDR) mouse models of ovarian carcinoma. Figures combined and reproduced from [120].120