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Box and whisker plots of metabolites from lymph (white) or plasma (black) that change in a statistically significant fashion (p<0.01, t-test) in matched samples from either fluid.
Highlighted are key metabolites that had been previously shown to change in human and rat plasma upon trauma and haemorrhage (A)12,13, sulphur metabolism (B) and glycolysis (C), a proxy for metabolic acidosis and a prognostic marker of survival upon trauma/haemorrhagic shock21.
