Pearson’s linear correlation coefficients were calculated for all the metabolites in lymph- and plasma-matched samples from the same patient (n=5).
Though preliminary, these results indicate that more than 150 metabolites showed correlations more than /0.75/ (p<0.05) (Online Supplementary Table I), suggesting that the two fluids are in metabolic equilibrium after trauma and haemorrhage in the tested samples. Only a subset of metabolites, including γ-glutamyl taurine (gamma-glutamyl cycle), show opposite trends in matched samples, indicating that this metabolite is selectively exchanged in either fluid after trauma/haemorrhagic shock.