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. 2016 May 19;14(1):728–736. doi: 10.3892/mmr.2016.5311

Figure 4.

Figure 4

Evaluation of histopathological alterations in the ischemic penumbra and the core zone by H&E staining. (A-C) H&E staining presenting gross histopathological alterations in normal, ischemic penumbra and the ischemic core at 12, 24 and 72 h post-reperfusion in the three groups. Black arrows indicate nuclear shrinkage, and the red arrows indicate neuronal vacuolization. Magnification, ×300. Scale bar =50 µm. H&E, hematoxylin and eosin; S, sham; IR, ischemia-reperfusion; I, z-fluoromethylketone.

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