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. 2016 May 5;14(1):234–242. doi: 10.3892/mmr.2016.5212

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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(A) Capillary density was measured using anti-von Willebrand factor immunohistology 21 days after transplantation. Blue staining shows the nuclei; brown staining shows the capillaries. Magnification, ×200. (B) The capillary density in the AFMSC and Akt-AFMSC groups was significantly higher than in the control group. ^*P<0.05 vs. control; ^#P<0.05 vs. AFMSCs. (C) VEGF secretion in recipient hearts was assessed by western blotting. (D) The levels of VEGF in the Akt-AFMSC group was significantly higher compared with that in control group. ^*P<0.05 vs. control; ^#P<0.05 vs. AFMSCs. GAPDH, glyceraldehyde-3-phosphate dehydrogenase; VEGF, vascular endothelial growth factor; AFMSCs, amniotic fluid-derived mesenchymal stem cells.