Table 2. Univariate relationships between each retinal outcome variable and covariates in control (MS disability = 0) and MS eyes with and without optic neuritis. Each cell contains the beta coefficient (95% confidence interval) for the outcome in that row as a function of the covariate in that column adjusted for within subject correlation using GEE models. * p < 0.05; ** p < 0.005.
| Age (Years) | Male Gender |
MS disability (Control = 0) |
Optic Neuritis | RNFLT (μm) | |
|---|---|---|---|---|---|
| RNFL thickness (μm) | 0.23 (0.001, 0.470)* |
1.66 (−4.21, 7.52) |
−3.75 (−5.42, −2.07)** |
−14.45 (−23.45, −5.45)** |
N/A |
| Total blood vessel diameter (μm) | −0.72 (−4.25, 2.82) |
46.55 (−24.06, 117.17) |
−61.48 (−89.08, −33.87)** |
−60.97 (−127.18, 5.24) |
2.97 (0.62, 5.33)* |
| Total blood vessel number | −0.06 (−0.11, 0.00) |
0.75 (−0.56, 2.06) |
−1.36 (−1.80, −0.92)** |
−0.74 (−1.92, 0.44) |
0.03 (−0.01, 0.07) |
| Average blood vessel diameter (μm) | 0.22 (0.03, 0.42)* |
0.76 (−3.14, 4.66) |
1.42 (0.00, 2.83)* |
1.81 (−1.78, 5.40) |
0.08 (−0.04, 1.61) |