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. 2016 May 4;14(1):33–40. doi: 10.3892/mmr.2016.5209

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Copyright: © Lee et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Histopathological findings of the proband. (A) Semi-thin transverse sections revealed almost complete loss of large MFs with preserved medium- and small-sized MFs. Toluidine blue stain; magnification, x400. (B) Histogram demonstrates a unimodal distribution pattern of MFs with a diameter >8 μm, which comprised 0.9% of the total MFs. (C and D) Electron micrographs (magnification, ×3,000 and ×10,000, respectively) indicated that the remaining MFs had focal abnormalities of myelinated and unmyelinated axons, with occasional rarefaction. MFs, myelinated fibers.