Table III.
Comparison of SNP array vs. other techniques.
| Authors/type of study Total number of samples studied | Techniques used in the study | HMs detected | Refs | |
|---|---|---|---|---|
| Grinschgl et al; Retrospective cohort | 150, early gestational loss | Morphology in combination with flow cytometry | 5 | (22) |
| Chiang et al; Products of conception | 40 (13 CHMs, 13 PHMs, 13 non-molar abortions and an equivocal hydropic abortion) | Polymorphic deletion probe, fluorescence in situ hybridization | 26 (5 CHMs, 13 PHMs, placental androgenetic/biparental mosaicism) | (15) |
| Furtado et al; Retrospective cohort | 102 cases referred for molar pregnancy testing | DNA microsatellites (short tandem repeats) | 31 CHMs; 17 PHMs | (14) |
| The present study; Retrospective cohort | 66 villous tissue and two twin tissue samples, not considered to be HMs according to the first diagnosis of experienced obstetricians | Affymetrix CytoScan® 750K array | 9 (3 CHMs, 6 PHMs) | – |
SNP, single nucleotide polymorphism; (C/P)HM, (complete/partial) hydatidiform mole.