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. Author manuscript; available in PMC: 2016 Jun 23.
Published in final edited form as: ACS Infect Dis. 2016 Jan 20;2(3):173–179. doi: 10.1021/acsinfecdis.5b00130

Figure 2.

Figure 2

Effect of ethyl ester hydrolysis on potency of compounds R11 (A) and R7 (B). RAW cells or RAW cell lysates were incubated with the indicated concentration of inhibitor. Probe BMV109 was used, as indicated in Figure 1, to label remaining cathepsin activity; disappearance of fluorescent signal corresponds to inhibition of cathepsin.