Figure 4.
Exercise, regardless of controllability, increases ΔFosB in the medial dorsal striatum (DS) and nucleus accumbens (NAc). A) Figure from the atlas of Paxinos and Watson showing the regions analyzed in the DS, NAc core (NAcC) and NAc shell (NAcS). B) Six weeks of voluntary (VR) of forced (FR) running increased ΔFosB in the medial DS, NAcC, and NAcS, but not the lateral DS (* p < 0.05 relative to Locked controls). C-E) Representative photomicrographs depicting immunostaining of ΔFosB in the medial dorsal striatum. F-H) Representative photomicrographs depicting immunostaining of ΔFosB in the NAcC. Bars represent group means ± SEM.