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Figure 2. Anti-B7-H1 antibody inhibition of tumor growth in vivo.
Lewis lung carcinoma (LLC) cells were subcutaneously injected into C57BL/6 mice
to form xenograft tumors. Anti-B7-H1 or vehicle control (LLC injected group)
was administered intravenously every 5 days thereafter. A,
Tumor growth was monitored every 5 days by calculating tumor area, which was
compared between the anti-B7-H1 and control groups. **P<0.01, compared with
the control group (ANOVA). B, Representative images of
xenograft tumors on day 30 after LLC injection in the control and anti-B7-H1
groups.