Fig. 2.
Generation of hepatocyte-specific Lpl knockout mice. A: PCR analysis of tail genomic DNA distinguishing the Lplflox allele and WT allele. PCR products in the size of 515 bp and 465 bp correspond to the floxed and WT alleles, respectively. Genotypes are indicated above each lane. F, floxed allele. B: The adult LPLΔhep mice displayed a substantial and tissue-specific reduction in Lpl mRNA levels in the liver (n = ∼4–6 per group). sWAT, subcutaneous white adipose tissue; vWAT, visceral white adipose tissue.