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Liver LPL regulated plasma lipid metabolism in HFD-induced obese mice. Male control and LplΔhep mice were fed a HFD for 3 months starting from 3 weeks of age. A: Body weight was not affected in LplΔhep mice after ∼2–6 months of HFD feeding. B: The TG and TC contents in the liver were not affected in obese mice by the deletion of hepatic Lpl. C: Fasting plasma lipid levels after 3 months of HFD feeding. Results represent the mean ± SEM. *P < 0.05 versus control; n = ∼6–8 for each group.
