Table 2.
compound/drug | dose mg/kg × days | % suppression in parasitemia (% activity)
|
cure | ||
---|---|---|---|---|---|
day 7 | day 10 | day 14 | |||
chloroquine | 50mg×3 | 100 | 100 | 100 | 3/4 |
1 | 10mg×3 | 100 | 100 | 90 | 1/4 |
2 | 30mg×3 | 100 | 83 | 67 | 0/4 |
10mg×3 | 57 | 35 | 32 | 0/4 | |
3 | 30mg×3 | 93 | 84 | 48 | 0/3 |
10mg×3 | 61 | 51 | 8 | 0/4 |
Oral treatment, vehicle = 0.1 N HCl.