Table 1.
Evaluation of Analogues Against P. falciparum
| compound | W2 clone IC50 (ng/mL) |
D6 clone IC50 (ng/mL) |
|---|---|---|
| manzamine A (1) | 13.5 | 25.0 |
| B (6) | 5550 | 3510 |
| iso BC (10) | 4190 | 920 |
| cis AB (5a) | 1270 | 930 |
| trans AB (5b) | 2770 | 1020 |
| ABCE (14) | 520 | 270 |
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