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. 2016 Jun 23;11(6):e0158307. doi: 10.1371/journal.pone.0158307

Table 6. Univariate analysis of progression-free survival and overall survival in patients with the EGFR mutation.

Parameter No. of patients Progression-free survival Overall survival
Mean survival time(months ±SE) P value Mean survival time(months ±SE) P value
Age
<64 57 13.27±2.04 0.504 30.45±1.65 0.503
≥64 34 14.77±1.61 27.42±1.93
Sex
Male 34 13.90±1.90 0.869 27.68±1.85 0.494
Female 57 14.05±1.64 30.22±1.66
Smoker
+ 48 11.57±1.19 0.147 27.79±1.52 0.344
- 43 16.34±2.09 30.95±2.02
ECOG performance status
0/1 73 14.98±1.51 0.215 30.57±1.49 0.236
2/3/4 18 9.58±1.35 25.20±3.03
Serum CEA level
Normal(≤5) 31 18.72±2.65 0.049 33.31±2.30 0.078
High(>5) 60 11.75±1.18 27.07±1.38
Serum LDH level
High 14 6.71±0.91 0.000 21.87±2.81 0.002
Normal 77 16.09±1.54 31.07±1.48
TLGT
<104.65 57 14.91±1.57 0.215 30.87±1.66 0.506
≥104.65 34 12.98±2.09 26.77±1.95
TLGWBR
<259.85 59 16.66±1.57 0.000 31.83±1.61 0.018
≥259.85 32 9.84±1.85 24.62±1.87

Abbreviations: ECOG: Eastern Cooperative Oncology Group; TLGT: primary tumor total lesion glycolysis (TLG); TLGWBR: whole-body total TLG determined using the Response Evaluation Criteria In Solid Tumors 1.1 criteria.