Table 6. Univariate analysis of progression-free survival and overall survival in patients with the EGFR mutation.
Parameter | No. of patients | Progression-free survival | Overall survival | ||
---|---|---|---|---|---|
Mean survival time(months ±SE) | P value | Mean survival time(months ±SE) | P value | ||
Age | |||||
<64 | 57 | 13.27±2.04 | 0.504 | 30.45±1.65 | 0.503 |
≥64 | 34 | 14.77±1.61 | 27.42±1.93 | ||
Sex | |||||
Male | 34 | 13.90±1.90 | 0.869 | 27.68±1.85 | 0.494 |
Female | 57 | 14.05±1.64 | 30.22±1.66 | ||
Smoker | |||||
+ | 48 | 11.57±1.19 | 0.147 | 27.79±1.52 | 0.344 |
- | 43 | 16.34±2.09 | 30.95±2.02 | ||
ECOG performance status | |||||
0/1 | 73 | 14.98±1.51 | 0.215 | 30.57±1.49 | 0.236 |
2/3/4 | 18 | 9.58±1.35 | 25.20±3.03 | ||
Serum CEA level | |||||
Normal(≤5) | 31 | 18.72±2.65 | 0.049 | 33.31±2.30 | 0.078 |
High(>5) | 60 | 11.75±1.18 | 27.07±1.38 | ||
Serum LDH level | |||||
High | 14 | 6.71±0.91 | 0.000 | 21.87±2.81 | 0.002 |
Normal | 77 | 16.09±1.54 | 31.07±1.48 | ||
TLGT | |||||
<104.65 | 57 | 14.91±1.57 | 0.215 | 30.87±1.66 | 0.506 |
≥104.65 | 34 | 12.98±2.09 | 26.77±1.95 | ||
TLGWBR | |||||
<259.85 | 59 | 16.66±1.57 | 0.000 | 31.83±1.61 | 0.018 |
≥259.85 | 32 | 9.84±1.85 | 24.62±1.87 |
Abbreviations: ECOG: Eastern Cooperative Oncology Group; TLGT: primary tumor total lesion glycolysis (TLG); TLGWBR: whole-body total TLG determined using the Response Evaluation Criteria In Solid Tumors 1.1 criteria.