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. 2016 Jun 23;11(6):e0157756. doi: 10.1371/journal.pone.0157756

Table 4. Price of medicines by countries where tested, by number of months of income needed to pay for a course of treatment or a year of treatment for chronic conditions by monthly minimum wage (MMW), monthly income per capita (MIPC)) in US$.

(All MNW and MIPC figures above 3 months have been rounded)a.

Argentina Brazilb Chile Colombia Mexico Peru
GDP in purchasing power parity (PPP) (World Bank, 2014) 12.568c 15,110 21,980 12,743 16,287 11,438
NME and Dosage
Aflibercept, 8 injections per year
 Price 30,410 15,259 10,882 10,122 NI --
 MMW 58 46 28 33 NI --
 MIPC 25 16 8 16 NI --
Apixaban, Two, 5 mg pills per day (730 per year).
 Price 1,858 1,259 1,714 1,294 1,536 R, NA
 MMW 3.5 3.8 5 4 14 --
 MIPC 1.5 1.5 0.9 2 2 --
Azilsartan medoxonil, 80 mg once a day (365 pills per year).
 Price R, NA -- R, NA -- 1,026 R, NA
 MMW -- -- -- -- 10 --
 MIPC -- -- -- -- 1.2 --
Belatacept, 10 mg per Kg per treatment. A person weighing up to 50 Kg needs 2 vials per treatment, and 16 treatments per year.
 Price 42,508 3,293 R, NA -- R, NA --
 MMW 81 10 -- -- -- --
 MIPC 35 4 -- -- -- --
Belimumab, 10 mg/Kg at 2-week interval for the first 3 doses and 4 weeks intervals thereafter. For a total of 15 treatments per year.
 Price N I 20,995 7,725 R, NA NI NR, GSK says it is A
 MMW -- 64 20 -- -- --
 MIPC -- 23 6 -- -- --
Crizotinib -- R, NA -- -- --
Indacaterol, 75 μg once a day
 Price
  150μg 798 -- 435 878 -- NI
  300μg 844 -- 809 NA -- NI
 MMW
  150μg 1.5 -- 1.1 3. -- --
  300μg 1.6 -- 2.5 NA -- --
 MIPC
  150 μg 0.6 -- 0.5 1.3 -- --
  300μg 0.7 -- 0.6 NA -- --
Ipilimumab, 3mg/kg IV infusion over 90 minutes every 3 weeks for 4 cycles
 Price 175,697 100,189 96,212 -- -- NI
 MMW 336 305 249 -- -- NI
 MIPC 143 107 74 -- -- NI
Linagliptin, 5 mg once a day
 Price 1,012 -- -- -- 1,120 NI
 MMW 1.9 -- -- -- 10 NI
 MIPC 0.8 -- -- -- 1.3 NI
Pasireotide, 600 or 900μg twice a day
 Price
  600μg 143,309 R, A? -- -- 88,061 --
  900μg 164,799 -- -- -- 99,413 --
 MMW
  600μg 274 -- -- -- 793 --
  900μg 315 -- -- -- 896 --
 MIPC
  600μg 117 -- -- -- 113 --
  900μg 134 -- -- -- 116 --
Pertuzumab, Initial dose 840mg as a 60-minute IV infusion, followed every 3 weeks thereafter by 420mg as a 30 to 60 minute IV infusion
 Price -- 58,979 -- -- 73.713 R, A?
 MMW -- 179 -- -- 644 --
 MIPC -- 75 -- -- 85 --
Regorafenib, 4 tablets a day, 21 days of 28-day cycle
 Price 19,584 NI -- -- -- --
 MMW 37 -- -- -- -- --
 MIPC 16 -- -- -- -- --
Rilpivirine, For HIV-1 infection in adults who have never taken HIV therapy R, A? NR, NA NR, A? -- R, A? --
Rivaroxavan, 10 mg once a day (Knee = 12 days; Hip = 35 days)
 Price Knee 162 42.6 55.6 170 59 60
 MMW 0.3 0.1 0.1 0.6 1 0.2
 MIPC 0.1 0.1 0.04 0.3 0.1 0.1
 Price Hip 476 124 162 496 171 160
 MMW 0.9 0.4 0.4 1.6 2 1
 MIPC 0.4 0.1 0.1 0.8 0.2 0.3
Roflumilast, One tablet 500 mcg per day
 Price -- 993 -- -- -- --
 MMW -- 3 -- -- -- --
 MIPC -- 1 -- -- -- --
Taliglucerasa alfa, 60 units/kg IV every 2 weeks, 26 treatments per year
 Price -- -- 266,960 -- -- --
 MMW -- -- 584 -- -- --
 MIPC -- -- 203 -- -- --
Telaprevir, 1125 mg twice a day, for 12 weeks
 Price 52,061 44,554 -- -- -- --
 MMW 99 135 -- -- -- --
 MIPC 42 48 -- -- -- --
Teriflunomide -- -- R, A? -- R, A? --
Ticagrelor, 90 mg twice a day
 Price 2,681 1,407 -- -- 1,879 --
 MMW 5 4 -- -- 17 --
 MIPC 2 1.5 -- -- 1.8 --
Tofacitinib, 5mgr twice a day
 Price 45,252 NR, NA N I 13,504 18,308 R, A?
 MMW 86.5 -- -- 44 165 --
 MIPC 37 -- -- 21 22 --
Vandetanib, 300 mg once a day
 Price 213,618 117,848 -- -- NR, A? --
 MMW 408 358 -- -- -- --
 MIPC 174 126 -- -- -- --

Information regarding the methodology to determine the MMW and MIPC can be found in Homedes and Ugalde.10 In Ecuador there was information only for Indacaterol, and to simplify the table we have not included the information and is available from corresponding author.

a For cells with no information, no clinical trials were conducted in the country or the product is not available. A = Available, A? = could not confirm if the product was available in the specific country, NA = Not Available; NI = No information available: R = registered: NR = Not registered

bIn Brazil, Anvisa publishes a list of maximum prices for the consumer that does not include taxes. The tax rate varies by state from 0–19%. We have included the maximum tax rate to the Anvisa prices.

c All GDP data are reported in PPP which are in US dollars and based on Atlas methodology used by the IMF and the World Bank. The Argentina GDP per capita is based on data officially reported by the National Statistics and Censuses Institute of Argentina that do not estimate the PPP. The International Monetary Fund (IMF) has called on Argentina to adopt measures to address the quality of official GDP and consumer price index data. More information available in http://data.worldbank.org/indicator/NY.GDP.PCAP.PP.KD