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. 2016 Jun 23;11(6):e0157970. doi: 10.1371/journal.pone.0157970

Fig 1. Survival after lethal rTcdA challenge in mice.

Fig 1

Kaplan-Meier plot of survival following lethal challenge with rTcdA alone, or treatment with CANmAbA4 at either 250 μg or 50 μg dose in comparison to the CDA1 anti-TcdA and polyclonal (pAb anti-TcdA) control. Following lethal challenge, mice (n = 10) were monitored and sacrificed according to approved protocols. Statistical analysis (Log-rank Test) using GraphPad prism 5 indicated that all antibody treated groups had statistically significant higher survival rate compared to control group (rTcdA alone) (P<0.001). There is no significant difference in survival rate among antibody treated groups.