Table 1. Virolysis patterns of GI norovirus strains after exposure to ethanol and Isopropanol.
Reduction in RNA titer (log10 RNA copies/ml)1 | ||||||||
---|---|---|---|---|---|---|---|---|
Genogroup | Strain ID | Genotype | 50% Ethanol | 70% Ethanol | 90% Ethanol | 50% Isopropanol | 70% Isopropanol | 90% Isopropanol |
GI | 8FIIb (4–3) | GI.1 | 0.1 ± 0.2 | 2.5 ± 0.7 | 2.6 ± 0.7 | 0.0 ± 0.4 | 0.1 ± 0.5 | 0.4 ± 0.4 |
17–6 | GI.1 | 0.1 ± 0.4 | 1.9 ± 0.0 | 1.8 ± 0.1 | 0.0 ± 0.1 | 0.0 ± 0.1 | 0.0 ± 0.2 | |
34–6 | GI.1 | 0.0 ± 0.4 | 2.0 ± 0.3 | 1.2 ± 0.2 | 0.0 ± 0.4 | 0.0 ± 0.3 | 0.0 ± 0.5 | |
2010746440 | GI.2 | 0.0 ± 0.3 | 0.5 ± 0.1 | 3.9 ± 0.1 | 0.0 ± 0.2 | 0.7 ± 0.6 | 0.7 ± 0.6 | |
2010746435 | GI.3b | 0.1 ± 0.2 | 0.4 ± 0.3 | 3.8 ± 0.1 | 0.0 ± 0.2 | 0.0 ± 0.2 | 1.4 ± 0.2 | |
2010746565 | GI.3b | 0.1 ± 0.1 | 0.2 ± 0.2 | 2.1 ± 0.2 | 0.0 ± 0.1 | 0.0 ± 0.2 | 1.7 ± 0.6 | |
2013775245 | GI.3b | 0.0 ± 0.3 | 3.5 ± 0.7 | 3.5 ± 0.7 | 0.2 ± 0.1 | 0.0 ± 0.2 | 0.1 ± 0.2 | |
2013843465 | GI.3b | 0.4 ± 0.7 | 2.9 ± 0.5 | 3.2 ± 0.9 | 0.5 ± 0.7 | 0.4 ± 0.7 | 0.8 ± 0.5 | |
2010746333 | GI.6 | 0.0 ± 0.0 | > 1.8 | > 1.8 | 0.2 ± 0.2 | 0.8 ± 0.7 | > 1.8 | |
2013751712 | GI.6 | 0.0 ± 0.2 | > 1.9 | > 1.9 | 0.0 ± 0.1 | 0.6 ± 0.1 | > 1.9 | |
2013751688 | GI.6 | 1.2 ± 0.4 | 2.3 ± 0.5 | 2.4 ± 0.5 | 0.3 ± 0.1 | 1.5 ± 0.6 | 2.3 ± 0.3 | |
2013751693 | GI.6 | 0.5 ± 0.5 | 2.1 ± 0.4 | 2.0 ± 0.2 | 0.0 ± 0.4 | 1.4 ± 0.5 | 1.4 ± 0.5 | |
2010746327 | GI.7 | 0.1 ± 0.1 | 1.0 ± 0.5 | 3.4 ± 0.3 | 0.5 ± 0.1 | 1.6 ± 0.3 | 3.4 ± 0.3 | |
2011755567 | GI.7 | 0.0 ± 0.1 | 0.2 ± 0.1 | 3.3 ± 0.7 | 0.0 ± 0.1 | 0.0 ± 0.2 | 0.4 ± 0.2 | |
Average reduction | 0.9 ± 0.9 | 1.2 ± 1.1 | 1.4 ± 0.9 | 0.6 ± 0.7 | 0.3 ± 0.4 | 1.0 ± 0.8 |
1: Reduction in RT-qPCR titer is expressed as the mean ± standard deviation of four replicates from two independent experiments