Table 2. Virolysis patterns of GII norovirus strains after exposure to ethanol and isopropanol.
- | Reduction in RNA titer (log10 RNA copies/ml)1 | |||||||
---|---|---|---|---|---|---|---|---|
Genogroup | Strain ID | Genotype | 50% Ethanol | 70% Ethanol | 90% Ethanol | 50% Isopropanol | 70% Isopropanol | 90% Isopropanol |
GII | 2010746610 | GII.1 | 0.2 ± 0.1 | 0.3 ± 0.2 | 0.7 ± 0.3 | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.4 ± 0.1 |
2010746618 | GII.2 | 0.4 ± 0.2 | 0.4 ± 0.2 | 0.7 ± 0.1 | 0.2 ± 0.1 | 0.2 ± 0.2 | 0.3 ± 0.2 | |
2013775428 | GII.43 | 2.3 ± 0.2 | 2.3 ± 0.3 | 2.4 ± 0.1 | 2.0 ± 0.5 | 0.9 ± 0.3 | 2.4 ± 0.1 | |
2013775418 | GII.43 | 1.2 ± 0.5 | 2.5 ± 0.5 | 2.7 ± 0.4 | 1.4 ± 0.3 | 0.9 ± 0.2 | 1.5 ± 0.4 | |
2010746350 | GII.44 | 0.4 ± 0.1 | 0.5 ± 0.2 | 1.4 ± 0.3 | 0.4 ± 0.1 | 1.0 ± 0.5 | 2.4 ± 0.4 | |
2010746173 | GII.44 | 0.2 ± 0.1 | 0.5 ± 0.4 | 0.9 ± 0.1 | 0.0 ± 0.2 | 0.0 ± 0.0 | 1.0 ± 0.3 | |
20107465262 | GII.44 | 0.4 ± 0.2 | 0.4 ± 0.2 | 1.6 ± 0.3 | 0.5 ± 0.2 | 0.5 ± 0.1 | 1.5 ± 0.1 | |
2013775232 | GII.45 | 2.0 ± 0.3 | 2.1 ± 0.1 | 2.2 ± 0.1 | 0.2 ± 0.1 | 0.1 ± 0.2 | 2.1 ± 0.6 | |
2013751795 | GII.45 | 1.1 ± 0.2 | 2.2 ± 0.5 | 1.6 ± 0.2 | 1.0 ± 0.2 | 0.5 ± 0.3 | 0.9 ± 0.3 | |
2013843445 | GII.45 | 1.8 ± 0.8 | 1.9 ± 0.7 | 2.4 ± 0.2 | 1.1 ± 0.3 | 0.4 ± 0.3 | 1.8 ± 0.2 | |
2013843449 | GII.45 | 2.5 ± 0.4 | 3.0 ± 0.2 | 3.1 ± 0.3 | 1.8 ± 0.3 | 0.7 ± 0.1 | 1.7 ± 0.2 | |
2010746514 | GII.7 | 0.1 ± 0.0 | 0.4 ± 0.1 | 0.7 ± 0.1 | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.8 ± 0.8 | |
2012706250 | GII.12 | 0.0 ± 0.1 | 0.1 ± 0.1 | 0.7 ± 0.1 | 0.0 ± 0.2 | 0.0 ± 0.1 | 0.0 ± 0.2 | |
2010746037 | GII.12 | 0.0 ± 0.2 | 0.0 ± 0.1 | 0.2 ± 0.2 | 0.0 ± 0.2 | 0.0 ± 0.1 | 0.0 ± 0.1 | |
2010746401 | GII.12 | 0.3 ± 0.3 | 1.4 ± 0.1 | 1.6 ± 0.1 | 0.2 ± 0.1 | 0.0 ± 0.2 | 0.4 ± 0.1 | |
2010746174 | GII.13 | 0.3 ± 0.1 | 0.4 ± 0.1 | 0.2 ± 0.2 | 0.5 ± 0.2 | 0.5 ± 0.1 | 0.0 ± 0.2 | |
Average reduction | 0.9 ± 0.5 | 1.2 ± 1.1 | 1.4 ± 0.9 | 0.6 ± 0.7 | 0.3 ± 0.4 | 1.0 ± 0.8 |
1: Reduction in RT-qPCR titer is expressed as the mean ± standard deviation of four replicates from two independent experiments
2: Sample was depleted and no full ORF2 sequence was obtained
3: GII.4 Den Haag
4: GII.4 New Orleans
5: GII.4 Sydney