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Schematic diagram of miRNA biogenesis. Pri-miRNAs are cleaved by the Drosha/DGCR8 complex producing pre-miRNA. Exp5 transports pre-miRNAs into the cytoplasm that are then processed by Dicer and Ago2/RISC complex to form mature miRNA. Adapted from [13]. Copyright adapted with permission from “Development”, via DOI:- http://dev.biologists.org/content/138/9/1653.long/.
