Table 2.
Paclitaxel recovery in arterial tissue
| p i | Paclitaxel in tissue | ||||
|---|---|---|---|---|---|
| [atm] | n | [μg] | [% of dose] | [μg/g] | |
| 1 | 13 | 18.64 (14.29–31.74) | 1.68 (1.16–2.76) | 792.7 (520.2–1211) | |
| Healthy | 2 | 13 | 22.26 (18.37–31.55) | 2.04 (1.69–2.42) | 823.6 (549.6–2059) |
| arteries | 6 | 13 | 20.83 (8.78–52.94) | 2.07 (0.88–5.59) | 875.3 (756.0–1493) |
| p* | 0.7906 | 0.6419 | 0.5382 | ||
| 1 | 6 | 2.51 (1.69–6.57)†† | 0.40 (0.26–0.71)†† | 212.4 (136.4–296.1)†† | |
| Atherosclerotic | 2 | 10 | 9.17 (3.88–11.22)†† | 1.12 (0.33–1.77)†† | 429.0 (132.1–616.6)† |
| arteries | 6 | 6 | 16.22 (13.04–27.07) | 2.65 (1.30–4.29) | 926.8 (644.9–1114) |
| p* | 0.0038 | 0.0081 | 0.0106 |
Data are given as median and (IQR)
p i, inflation pressure
*p-value of Kruskal-Wallis test (1 vs. 2 vs. 6 atm)
† p < 0.05
†† p < 0.01 in Mann-Whitney test (atherosclerotic vs. healthy arteries at the same inflation pressure)