FIGURE 4.

Formation of TREK-1-L/TREK-2-S heterodimers. Xenopus oocytes were injected with different ratios of TREK-1-L and TREK-2-S cRNA. Currents were recorded from inside-out membrane patches as described in Fig. 3. Unitary currents and single channel conductances were calculated from patches containing one or two channels and plotted in the function of injected RNA ratios. For comparison, the averages (± S.D.) of TREK-1, TREK-2, and TREK-2-S/TREK-1-L tandem channel unitary currents were also plotted.