FIGURE 9.

TREK-1 and TREK-2 form heterodimers in HEK293T cells. HEK293T cells were transfected with plasmids coding TREK-1 (circles), TREK-2 (triangles), or TREK-1-T2A-TREK-2 (diamonds). The sensitivity of the currents to extracellular acidification (pH 7.4 to pH 6.4) and RR application (30 μm) was plotted against each other. Averages of the three groups (empty diamonds) are shown with error bars representing S.E. The straight line connects the averages of the groups expressing TREK-1 or TREK-2 homodimers, respectively.