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. 2016 Jun 8;104(1):65–72. doi: 10.3945/ajcn.116.130393

TABLE 2.

RRs (95% CIs) of deciles of the food-based Food Quality Score for risk of CAD1

D1 D2 D3 D4 D5 D6 D7 D8 D9 D10 P-trend
Total CAD
 NHS
  Cases, n 290 258 304 317 299 295 262 258 255 201
  Age and energy adjusted 1 0.71* 0.77* 0.79* 0.66* 0.65* 0.58* 0.51* 0.50* 0.42 (0.35, 0.51)* <0.001
  Multivariable adjusted2 1 0.76* 0.86 0.91 0.78* 0.80* 0.74* 0.65* 0.67* 0.58 (0.48, 0.70)* <0.001
  Above + BMI 1 0.76* 0.87 0.92 0.79* 0.80* 0.75* 0.66* 0.68* 0.60 (0.49, 0.72)* <0.001
 HPFS
  Cases, n 361 401 348 414 398 336 357 369 394 295
  Age and energy adjusted 1 0.92 0.81* 0.85* 0.80* 0.72* 0.78* 0.73* 0.62* 0.55 (0.47, 0.65)* <0.001
  Multivariable adjusted2 1 0.95 0.86 0.87 0.85* 0.77* 0.81* 0.81* 0.68* 0.63 (0.53, 0.74)* <0.001
  Above + BMI 1 0.95 0.86 0.97 0.85* 0.77* 0.82* 0.82* 0.70* 0.65 (0.55, 0.77)* <0.001
 NHS II
  Cases, n 70 64 61 58 44 58 46 42 35 27
  Age and energy adjusted 1 0.78 0.72 0.65* 0.51* 0.62* 0.50* 0.42* 0.36* 0.27 (0.17, 0.42)* <0.001
  Multivariable adjusted2 1 0.87 0.85 0.81 0.64* 0.83 0.69 0.60* 0.54* 0.43 (0.27, 0.68)* <0.001
  Above + BMI 1 0.87 0.85 0.81 0.65* 0.84 0.71 0.61* 0.56* 0.46 (0.28, 0.73)* <0.001
 Pooled
  Multivariable + BMI adjusted2 1 0.87* 0.86* 0.90 0.82* 0.80* 0.80* 0.73* 0.69* 0.61 (0.54, 0.69)* <0.001
Nonfatal CAD
 NHS
  Cases, n 238 197 234 249 224 225 206 298 197 156
  Age and energy adjusted 1 0.68* 0.75* 0.79* 0.64* 0.64* 0.59* 0.51* 0.51* 0.43 (0.35, 0.53)* <0.001
  Multivariable adjusted2 1 0.72* 0.82* 0.88 0.73* 0.76* 0.72* 0.63* 0.65* 0.57 (0.46, 0.71)* <0.001
  Above + BMI 1 0.72* 0.83* 0.89 0.73* 0.76* 0.73* 0.63* 0.66* 0.58 (0.47, 0.72)* <0.001
 HPFS
  Cases, n 215 233 215 230 202 175 199 192 157 145
  Age and energy adjusted 1 0.92 0.88 0.80* 0.73* 0.69* 0.77* 0.69* 0.61* 0.52 (0.44, 0.68)* <0.001
  Multivariable adjusted2 1 0.95 0.93 0.85 0.78* 0.72* 0.82 0.75* 0.65* 0.57 (0.46, 0.71)* 0.002
  Above + BMI 1 0.94 0.93 0.85 0.78* 0.72* 0.83 0.76* 0.67* 0.60 (0.48, 0.74)* 0.005
 NHS II
  Cases, n 62 60 55 55 41 55 35 35 34 26
  Age and energy adjusted 1 0.82 0.74 0.69 0.53* 0.67* 0.43* 0.39* 0.40* 0.29 (0.18, 0.46)* <0.001
  Multivariable adjusted2 1 0.92 0.87 0.86 0.67 0.89 0.60* 0.56* 0.59* 0.46 (0.29, 0.75)* <0.001
  Above + BMI 1 0.92 0.86 0.86 0.68 0.90 0.61* 0.57* 0.61* 0.49 (0.30, 0.80)* 0.002
 Pooled
  Multivariable + BMI adjusted2 1 0.84* 0.88 0.88 0.75* 0.76* 0.78* 0.68* 0.67* 0.56 (0.49, 0.65)* <0.001
Fatal MI
 NHS
  Cases, n 52 61 70 68 75 70 56 60 58 45
  Age and energy adjusted 1 0.86 0.85 0.80 0.76 0.69* 0.54* 0.51* 0.48* 0.39 (0.26, 0.59)* <0.001
  Multivariable adjusted2 1 0.98 1.03 1.02 0.99 0.97 0.83 0.79 0.79 0.66 (0.43, 1.00)* 0.008
  Above + BMI 1 0.98 1.05 1.06 1.02 0.99 0.85 0.81 0.82 0.69 (0.45, 1.04) 0.02
 HPFS
  Cases, n 146 168 133 185 196 162 158 177 137 150
  Age and energy adjusted 1 0.92 0.70* 0.81 0.82 0.73* 0.69* 0.73* 0.60* 0.60 (0.48, 0.76)* <0.001
  Multivariable adjusted2 1 0.94 0.76* 0.89 0.92 0.83 0.78* 0.87 0.71* 0.70 (0.56, 0.91)* 0.002
  Above + BMI 1 0.95 0.77* 0.89 0.92 0.84 0.79* 0.89 0.72* 0.72 (0.57, 0.92)* 0.004
 Pooled
  Multivariable + BMI adjusted2 1 0.96 0.85 0.94 0.95 0.89 0.82 0.87 0.76* 0.71 (0.58, 0.88)* <0.001
1

n = 71,415 for the NHS, n = 42,495 for the HPFS, and n = 93,131 for the NHS II. RRs were computed by use of the Cox proportional hazard model. 95% CIs for D2–9 are provided in Supplemental Table 3. *P < 0.05. CAD, coronary artery disease; D, decile; HPFS, Health Professionals Follow-Up Study; MI, myocardial infarction; NHS, Nurses’ Health Study; NHS II, Nurses’ Health Study II.

2

Values were adjusted for age, BMI, smoking, physical activity, family history of diabetes, energy intake, alcohol intake, postmenopausal hormone use (NHS and NHS II), and oral contraceptive use (NHS II).