TABLE 3.

Pooled multivariable RRs (95% CIs) of quintiles of original food-based Food Quality Score for total coronary artery disease, stratified by major risk factors¹

	Q1	Q2	Q3	Q4	Q5	P-trend	P-heterogeneity2
BMI, kg/m2
<25 (2574 cases)	1	0.90 (0.79, 1.02)	0.85 (0.75, 0.97)	0.77 (0.67, 0.87)	0.61 (0.53, 0.69)	<0.001
≥25 (4169 cases)	1	0.97 (0.89, 1.07)	0.88 (0.80, 0.97)	0.87 (0.78, 0.96)	0.78 (0.70, 0.87)	<0.001	0.006
Physical activity
METs < median (4960 cases)	1	0.95 (0.87, 1.03)	0.87 (0.80, 0.95)	0.83 (0.76, 0.92)	0.76 (0.69, 0.84)	<0.001
METs ≥ median (1900 cases)	1	0.91 (0.79, 1.05)	0.79 (0.68, 0.92)	0.74 (0.64, 0.86)	0.52 (0.45, 0.61)	<0.001	0.17
Smoking status
Nonsmoker (5790 cases)	1	0.93 (0.85, 1.01)	0.85 (0.78, 0.93)	0.82 (0.75, 0.90)	0.68 (0.62, 0.74)	<0.001
Current smoker (1070 cases)	1	1.06 (0.89, 1.26)	0.97 (0.80, 1.17)	0.86 (0.70, 1.06)	0.85 (0.67, 1.09)	0.006	0.33
Family history of MI
No (3681 cases)	1	0.96 (0.87, 1.06)	0.85 (0.77, 0.94)	0.84 (0.76, 0.94)	0.71 (0.64, 0.80)	<0.001
Yes (3179 cases)	1	0.95 (0.85, 1.06)	0.89 (0.80, 1.00)	0.83 (0.73, 0.93)	0.69 (0.61, 0.78)	<0.001	0.99

¹Adjusted for age, BMI, smoking, physical activity, family history of MI, energy intake, coffee intake, alcohol intake, and postmenopausal hormone use (Nurses’ Health Study only). RRs were computed with the Cox proportional hazard model. MET, metabolic equivalent of task; MI, myocardial infarction; Q, quintile.

²P-heterogeneity was tested by comparing the slopes of the food-based Food Quality Score when the score was modeled as a continuous variable at each stratification category.