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. 2016 May 29;173(14):2237–2249. doi: 10.1111/bph.13503

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© 2016 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Mdk‐Ab treatment accelerated fracture healing in mice. Biomechanical and μCT analysis of the fractured femurs on days 21 (d21) and 28 (d28). (A) Relative flexural rigidity of the fractured femur in comparison with intact femur. (B) BV/TV of the fracture callus. (C) TV of the fracture callus at the osteotomy gap. (D) Moment of inertia (Ix) of the fracture callus in bending axis x. (E) Representative μCT images from the fracture calli on day 21. *Significantly different from vehicle (P < 0.05) by Mann–Whitney U‐test. (n = 6–8 per group).