Table 1.

Mdk serum levels (pg·mL⁻¹) during fracture healing in 9‐month‐old mice

Days after operation	Vehicle	Mdk‐Ab
0	7.2 ± 12.3
4	63.8 ± 4.9*	8.9 ± 15.4
10	86.4 ± 7.3*	29.7 ± 31.7#
21	9.6 ± 16.7	n.d.

n.d., not detectable; day 0, pre‐operation value. (n = 4–7 per group; results presented as mean ± SD).

^* P < 0.05 for effect of fracture.

^# P < 0.05 for effect of Mdk‐Ab; Mann–Whitney U‐test.