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. 2016 Jun 2;173(14):2250–2262. doi: 10.1111/bph.13506

Figure 5.

Figure 5

Dexamethasone (Dex) regulates the expression of RANKL, OPG and Mig6 in osteoblastic cells. (a) qRT‐PCR measurements of mRNA expression of RANKL and OPG in primary osteoblastic cells treated with various concentrations of dexamethasone (10, 50, 250 and 1000 nM) for 48 h. *P < 0.05 versus control; Kruskal–Wallis test; n = 6 per group. (b) Immunostaining of Mig6 in bone marrow cavity: black arrow heads show positive stained osteoblasts. (b) The mean optical density of positive stained chondrocytes was quantified. *P < 0.05 versus control; Student's t‐test; n = 6 per group. Scale bar = 200 μm.