Table 6. The haplotype analysis on the risk of tuberculosis.
Haplotype | Control, n(%) | Case, n(%) | OR(95%Cl)a | P |
---|---|---|---|---|
rs2275913-rs3748067 | ||||
AG | 1401(45.90) | 1416(44.22) | 1 | |
GG | 1176(38.53) | 1285(40.13) | 1.12(1.00–1..25) | 0.046 |
GA | 469(15.37) | 493(15.4) | 1.09(0.94–1.27) | 0.265 |
AA | 6(0.20) | 8(0.25) | 1.28(0.42–3.87) | 0.667 |
rs10983755-rs10759932 | ||||
GT | 2159(70.74) | 2156(67.33) | 1 | |
AC | 846(27.72) | 909(28.39) | 1.08(0.96–1.21) | 0.198 |
GC | 36(1.18) | 120(3.75) | 3.43(2.34–5.05) | <0.001b |
AT | 11(0.36) | 17(0.53) | 1.42(0.65–3.09) | 0.375 |
aOR: odds ratio; CI: confidence interval, adjusted for age, sex, smoking and drinking.
bSignificant after the Bonferroni correction for multiple comparisons.