Figure 2. CA4 inhibited proliferation of human endothelial cells.
Cell proliferation was determined by MTT assay after being treated with CA4 for 48 h (A). Analysis of cell cycle in HUVECs after being treated with CA4 for 24 h (B). Cell proliferation was determined by MTT assay after being treated with CA4 for 48 h in the presence of VEGF (20 ng/mL) (C). Cell proliferation was determined by MTT assay after being treated with CA4 for 48 h in the presence of SUl498 (10 μM) (D). All data were represented as means ± SD, n = 3, *P < 0.05 versus control, **P < 0.01 versus control, ***P < 0.001 versus control.