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. 2016 Jun 24;6:28617. doi: 10.1038/srep28617

Figure 3. RBP-J cKO mice exhibited reduced CNV severity.

Figure 3

RBP-J cKO and control mice were subjected to laser coagulation with six laser burns in one eye (six mice for each group). Choroidal tissues were flat-mounted and stained with FITC-isolectin B4 7 and 14 days later, and examined under a laser-scanning confocal microscope (A), followed by reconstruction of the CNV lesions (B). The CNV volumes were compared between the two groups (C). The optic nerve head are labeled with red circle. Data are presented as mean ± SEM of six RPE/choroid from six mice (six laser burns in each RPE/choroid). *P < 0.05.